The patient died April 17, 1861. At the autopsy, the dura mater was found to be thickened and vascularised, covered on the inside with a thick pseudo-membranous layer; the pia mater thick, opaque, and adherent to the anterior lobes particularly the left lobe. The frontal lobe of the left hemisphere was soft over a great part of its extent; the convolutions of the orbital region, although atrophied, preserved their shape; most of the other frontal convolutions were entirely destroyed. The result of this destruction of the cerebral substance was a large cavity, capable of holding a chicken egg, and filled with serous fluid.
- Pierre Broca
describing the autopsy of a man who died from syphilis. Don’t get syphilis, kids. It will leave a chicken-egg sized hole in your brain